Henan Grubbs Chemical CO.LTD

Used In Antitumor And Antiviral Drugs
product details

The Grubbs catalyst produced by Henan Grubbs Chemical Co.,Ltd,Brand:Crystaline,was widely used in the production of antitumor and antiviral drugs.It is the only one factory who can produce Grubbs catalyst safely used in medicine in China.Its purity and activity has the same level with the USA made.
The following was brief  introduction of Grubbs catalyst used in the medicine and health care industry.

1、Synthesis of nucleoside analogues
Nucleoside analogues can participate in and interferes with bacteria (virus) of DNA or RNA replication, transcription or reverse transcription process, inhibit the growth and reproduction, so as to have capability for being drugs of antitumor and antiviral. It is an important subject in nucleic acid drug chemistry for Synthesis of bioactive chemical modified nucleosides and its derivatives . With the discovery of crystal1 catalyst  and continuing improvement, olefin metathesis reactions, especially n-cyclohexylmaleimide metathesis and cross metathesis reaction, it is widely used in construction of nucleoside analogues (or false) sugar sugar ring structure or connection more monomers to form a nucleoside analogues, such as widely used in the synthesis of, including carbocyclic nucleoside analogues, 2 ', 3 '- double DNA nucleoside, acyclic nucleosides, polycyclic nucleoside and nucleotide dimer and trimer.

2、Synthetic of erythropoietin, the simulation peptide
erythropoietin, the simulation peptide Is the key factor to determine the performance and function of erythropoietin.Erythropoietin is know as the most unique role , safe and reliable hemoglobin preparation so far . it has certain curative effect on renal anemia, aplastic anemia, multiple myeloma, paroxysmal nocturnal blood in the urine, etc. In addition, the application of erythropoietin can also reduce the amount of blood transfusion in the operation, and can be corrected to some extent caused by malignant tumor, chemotherapy, and rheumatoid arthritis, anemia, There is a broad prospect for the treatment and diagnosis of blood diseases characterized by low red blood cell formation and defects.In the global biotech drug market, erythropoietin restructuring drugs has a huge market capacity.

3、Catalytic synthesis of coenzyme Q10
Coenzyme Q10 is a fat-soluble antioxidant, it can activate human cells and cellular energy nutrition, with functions of improve human immunity, enhance anti-oxidation, anti-aging, and enhance the vitality of the human body, it widely used in diseases of the cardiovascular system medically, widely use-d for nutrition health care products and food additives at home and abroad.